Teaching assistant training program of the 2019 academic year
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มหาวิทยาลัยเชียงใหม่
Chemical Waste Management and Laboratory Safety Chiang Mai University 2019
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มหาวิทยาลัยเชียงใหม่
Laboratory Safety and Chemical Hygiene Plane Chiang Mai University 2018
ความสามารถ
ความสามารถทางภาษา
พูด (ดีมาก) อ่าน (ดีมาก) เขียน (ดีมาก)
พูด (ดี) อ่าน (ดี) เขียน (ดี)
ไทย คำ/นาที อังกฤษ คำ/นาที
รถยนต์ ,รถจักรยานยนต์ ,
รถจักรยานยนต์ ,
โครงการ / ผลงาน / เกียรติประวัติ / บุคคลอ้างอิง
ได้รับการตีพิมพ์ผลงานวิจัยลงในวารสารต่างประเทศ
Publication: Tayanee Panapimonlawat, Sukon Phanichphant and Saengrawee Sriwichai, “Electrochemical dopamine biosensor based on poly(3‐aminobenzyl amine) layer‐by‐layer self‐assembled multilayer thin film,” Polymers, 13, 2021, 1488.
Abstract
Dopamine (DA) is an important neurotransmitter which indicates the risk of several neurological diseases. The selective determination with low detection limit is necessary for early diagnosis and prevention of neurological diseases associated with abnormal concentration of DA. The purpose of this study is to fabricate a poly(3-aminobenzylamine)/poly(sodium 4-styrenesulfonate) (PABA/PSS) multilayer thin film for use as an electrochemical DA biosensor. The PABA was firstly synthesized using a chemical oxidation method of 3-aminobenzylamine (ABA) monomer with ammonium persulfate (APS) as an oxidant. For electrochemical biosensor, the PABA/PSS thin film was fabricated on fluorine doped tin oxide (FTO)-coated glass substrate using the layer-by-layer (LBL) self-assembly method. The optimized number of bilayers was achieved using SEM and cyclic voltammetry (CV) results. The electroactivity of the optimized LBL thin film toward detection of DA in neutral solution was studied by CV and amperometry. The PABA/PSS thin film showed good sensitivity for DA sensing with sensitivity of 6.922 nA·cm−2·µM−1 and linear range of 0.1–1.0 µM (R2 = 0.9934), with low detection limit of 0.0628 µM, long-term stability and good reproducibility. In addition, the selectivity of the PABA/PSS thin film for detection of DA under the common interferences (i.e., ascorbic acid, uric acid and glucose) was also presented. The prepared PABA/PSS thin film showed the powerful efficiency for future use as DA biosensor in real sample analysis. View Full-Text
Keywords: conducting polymer; poly(3-aminobenzylamine); dopamine; layer-by-layer self-assembly; biosensor